Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011733 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1SMN1; SMN2TSHR | |
| SCHEMBL7811934 | 0.80 | HCAR3 (0.51) | ALDH1A1MAPTMAPK1SMN1; SMN2LMNA | |
| SCHEMBL11271443 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTMAPK1SMN1; SMN2LMNA | |
| SCHEMBL8948382 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTMAPK1SMN1; SMN2TSHR | |
| SCHEMBL5164284 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTMAPK1SMN1; SMN2LMNA | |
| SCHEMBL28808502 | 0.74 | MAPK1 (0.53) | ALDH1A1MAPTMAPK1SMN1; SMN2LMNA | |
| SCHEMBL10936226 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1SMN1; SMN2LMNA | |
| SCHEMBL29392416 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL3378074 | 0.74 | EGFR (0.61) | ALDH1A1MAPTMAPK1SMN1; SMN2LMNA | |
| SCHEMBL127370 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTSMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5685881-A | Aromatic allylaminonitro compounds, hair dye compositions containing aromatic allylaminonitio compounds, and synthetic and natural fiber dyeing process | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1997-11-11 | — | — | US | disclosed |
| EP-0671900-B1 | ALLYLAMINO-NITROAROMATES | HENKEL KGAA (DE) | 1996-08-14 | — | — | EP | disclosed |