Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892087 | 0.83 | USP14 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8902350 | 0.82 | SIGMAR1 (0.36) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8893472 | 0.82 | TMEM97 (0.40) | SIGMAR1 | |
| SCHEMBL8902759 | 0.81 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL8903400 | 0.76 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL8894442 | 0.76 | — | — | |
| SCHEMBL8892587 | 0.75 | MAPK8 (0.32) | — | |
| SCHEMBL8902537 | 0.75 | SIGMAR1 (0.35) | SIGMAR1OPRM1 | |
| SCHEMBL10656985 | 0.75 | TMEM97 (0.40) | — | |
| SCHEMBL8894636 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043282-A2 | BENZOTHIAZOLINONES AS ANTI-ASTHMATIC AGENTS | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |