Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 1.00 |
| ▸ | HTR1B | P28222 | 13/20 | 1.00 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893980 | 0.85 | HTR1D (0.73) | HTR1DHTR1BBRD4 | |
| SCHEMBL8902545 | 0.81 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR7BRD4 | |
| SCHEMBL8686765 | 0.81 | HTR1D (1.00) | HTR1DHTR1BBRD4MPO | |
| SCHEMBL8903385 | 0.80 | HTR1D (0.98) | HTR1DHTR1BBRD4MPO | |
| SCHEMBL8901608 | 0.78 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL8901617 | 0.78 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL8686120 | 0.78 | HTR1D (1.00) | HTR1DHTR1BHTR1AHTR7MPO | |
| SCHEMBL8901244 | 0.78 | HTR1D (0.76) | HTR1DHTR1BHTR1AHTR7TUBB4A | |
| SCHEMBL8903278 | 0.78 | HTR1B (1.00) | HTR1DHTR1BHTR1A | |
| SCHEMBL8903284 | 0.78 | HTR1B (1.00) | HTR1DHTR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | claimed |
| WO-1997043281-A1 | THIOPHENE- AND FURAN-TRYPTAMINE DERIVATIVES | ALLELIX BIOPHARMACEUTICALS INC. (CA) | 1997-11-20 | — | — | WO | disclosed |