Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443493 | 0.87 | OPRM1 (0.69) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| SCHEMBL11546029 | 0.87 | OPRM1 (0.76) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| SCHEMBL9425443 | 0.86 | OPRM1 (0.63) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| Hydrochloric Acid SCHEMBL27864255 | 0.85 | OPRM1 (0.67) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| Water SCHEMBL8191777 | 0.85 | OPRM1 (0.67) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| SCHEMBL12128296 | 0.82 | DRD3 (0.68) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| SCHEMBL12126536 | 0.82 | BCHE (0.62) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| SCHEMBL3376047 | 0.79 | CNR2 (0.55) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| SCHEMBL10901912 | 0.78 | OPRM1 (0.63) | OPRM1DRD3KCNH2CHRM2HTR1A | |
| SCHEMBL12128305 | 0.78 | KCNH2 (0.75) | OPRM1DRD3KCNH2CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663148-A | ANTIINFLAMMATORY AGENTS OF OLIGOPEPTIDES FOR BACTERICIDES, FUNGICIDES, ANTICARCINOGENIC AGENTS, VIRICIDES OR AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1994007815-A2 | SMALL PEPTIDE ANAPHYLATOXIN RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1994-04-14 | — | — | WO | disclosed |
| WO-1994007518-A1 | ANAPHYLATOXIN RECEPTOR LIGANDS CONTAINING LIPOPHILIC RESIDUES | ABBOTT LABORATORIES (US) | 1994-04-14 | — | — | WO | disclosed |