Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 20/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.43 |
| ▸ | F10 | P00742 | 6/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891947 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8892934 | 0.88 | ITGB3 (0.43) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7456463 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7461432 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7461182 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8892999 | 0.83 | ITGB3 (0.41) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8893792 | 0.82 | ITGB3 (0.40) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8894165 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BF10 | |
| SCHEMBL8894310 | 0.79 | GPR119 (0.36) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7456679 | 0.79 | ITGB3 (0.57) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |