Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.73 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141321 | 1.00 | TACR1 (0.73) | TACR1FNTAFNTBGRIN2BOPRM1 | |
| SCHEMBL8548123 | 1.00 | TACR1 (0.73) | TACR1FNTAFNTBGRIN2BOPRM1 | |
| SCHEMBL8956796 | 0.93 | TACR1 (0.68) | TACR1FNTAFNTBGRIN2BOPRM1 | |
| SCHEMBL8460147 | 0.87 | TACR1 (0.60) | TACR1GRIN2BOPRM1OPRD1OPRK1 | |
| Dapitant SCHEMBL6437147 | 0.84 | TACR1 (1.00) | TACR1FNTAFNTBGRIN2BOPRM1 | |
| Dapitant SCHEMBL8543936 | 0.84 | TACR1 (1.00) | TACR1FNTAFNTBGRIN2BOPRM1 | |
| Dapitant SCHEMBL7582571 | 0.84 | TACR1 (1.00) | TACR1FNTAFNTBGRIN2BOPRM1 | |
| Dapitant SCHEMBL7768046 | 0.84 | TACR1 (1.00) | TACR1FNTAFNTBGRIN2BOPRM1 | |
| Dapitant SCHEMBL121135 | 0.84 | TACR1 (1.00) | TACR1FNTAFNTBGRIN2BOPRM1 | |
| Dapitant SCHEMBL13575759 | 0.84 | TACR1 (1.00) | TACR1FNTAFNTBGRIN2BOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631279-A | ANTAGONISTS OF NEUROKININ A | RHONE-POULENC RORER, S.A. (FR) | 1997-05-20 | — | — | US | disclosed |