⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28338954 | 0.67 | — | — | |
| SCHEMBL10869950 | 0.67 | — | — | |
| SCHEMBL902586 | 0.67 | — | — | |
| SCHEMBL5503133 | 0.67 | — | — | |
| SCHEMBL6272885 | 0.65 | — | — | |
| SCHEMBL689863 | 0.65 | — | — | |
| SCHEMBL8091274 | 0.65 | — | — | |
| SCHEMBL689545 | 0.65 | — | — | |
| SCHEMBL902775 | 0.63 | — | — | |
| SCHEMBL7224474 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256907-B1 | PROTEIN SYNTHESIS INHIBITOR, PROCESS FOR ITS ISOLATION, USE, AND PHARMACEUTIAL COMPOSITIONS CONTAINING IT | SANOFI S.A. (FR) | 1991-10-16 | — | — | EP | claimed |
| EP-0255424-B1 | IMMUNOTOXINS, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1991-09-18 | — | — | EP | claimed |
| US-5681707-A | USEFUL IN DIAGNOSING DISEASES RELATED TO METABOLISM OF THE BONES | TEIJIN LIMITED (JP) | 1997-10-28 | — | — | US | disclosed |
| US-5643735-A | IMMUNOLOGY | YUKA MEDIAS, CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0410004-B1 | IMMUNOASSAY OF HUMAN OSTEOCALCIN, REAGENT AND KIT THEREFOR | TEIJIN LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5506111-A | REACTING SAMPLE WITH SOLID PHASE AND LABELLED ANTIBODIES TO DIFFERENT EPITOPES OF HUMAN OSTEOCALCIN TO FORM COMPLEX, SEPARATING COMPLEX, MEASURING AMOUNT OF LABELLED ANTIBODY THEREIN, CORRELATING WITH AMOUNT OF OSTEOCALCIN PRESENT | TEIJIN LIMITED (JP) | 1996-04-09 | — | — | US | disclosed |
| EP-0700993-A1 | Anti-thymosin alpha 1 monoclonal antibody-producing hybridoma | YUKA MEDIAS Co., Ltd. (JP) | 1996-03-13 | — | — | EP | disclosed |
| EP-0646794-A1 | Method of immunological assaying of human osteocalcin, reagent and kit therefor, antibody to human osteocalcin, hybridoma producing said antibody, and method of producing it | TEIJIN LIMITED (JP) | 1995-04-05 | — | — | EP | disclosed |
| EP-0329794-B1 | METHOD FOR ASSAYING HUMAN LUNG SURFACE ACTIVE SUBSTANCE | TEIJIN LTD (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-5274122-A | Acidic derivatives of homocysteine thiolactone | MERCK & CO., INC. (US) | 1993-12-28 | — | — | US | disclosed |
| US-5162502-A | Immunotoxins | SANOFI (FR) | 1992-11-10 | — | — | US | disclosed |
| EP-0463571-A2 | Recombinant human osteocalcin | TEIJIN LIMITED (JP) | 1992-01-02 | — | — | EP | disclosed |
| US-5037960-A | Antitumor agents | SANOFI (FR) | 1991-08-06 | — | — | US | disclosed |
| EP-0410004-A1 | IMMUNOASSAY OF HUMAN OSTEOCALCIN, REAGENT AND KIT THEREFOR | TEIJIN LIMITED (JP) | 1991-01-30 | — | — | EP | disclosed |
| US-4981953-A | ANTITUMOR | SANOFI (FR) | 1991-01-01 | — | — | US | disclosed |
| EP-0329794-A1 | METHOD FOR ASSAYING HUMAN LUNG SURFACE ACTIVE SUBSTANCE | TEIJIN LIMITED (JP) | 1989-08-30 | — | — | EP | disclosed |
| EP-0256907-A1 | Protein synthesis inhibitor, process for its isolation, use, and pharmaceutial compositions containing it | SANOFI S.A. (FR) | 1988-02-24 | — | — | EP | disclosed |
| EP-0220899-A1 | Bifunctional linker | Immunomedics, Inc. (US) | 1987-05-06 | — | — | EP | disclosed |
| US-4340535-A | CANCER CELLS | C M INDUSTRIES (FR) | 1982-07-20 | — | — | US | disclosed |