Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467820 | 0.88 | — | — | |
| SCHEMBL8893351 | 0.86 | HPGD (0.37) | SMN1; SMN2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8894080 | 0.80 | — | — | |
| SCHEMBL8894588 | 0.72 | ITGB3 (0.42) | SMN1; SMN2TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8894594 | 0.71 | CYP1A2 (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9AHTT | |
| SCHEMBL8894573 | 0.71 | CYP1A2 (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9AHTT | |
| SCHEMBL7456463 | 0.61 | ITGB3 (0.49) | — | |
| SCHEMBL7293890 | 0.59 | MEN1 (0.30) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL24365233 | 0.58 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAALDH1A1MEN1KMT2A | |
| SCHEMBL7461829 | 0.58 | ITGB3 (0.45) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |