Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.42 |
| ▸ | F10 | P00742 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893356 | 0.85 | SMN1; SMN2 (0.42) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7456463 | 0.78 | ITGB3 (0.49) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7467481 | 0.77 | MAOA (0.41) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7456679 | 0.76 | ITGB3 (0.57) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8894594 | 0.76 | CYP1A2 (0.37) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8894573 | 0.76 | CYP1A2 (0.37) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8894267 | 0.73 | PRSS1 (0.51) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8892948 | 0.73 | SMN1; SMN2 (0.44) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL8894579 | 0.72 | SMN1; SMN2 (0.35) | TSHRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7456682 | 0.71 | PRSS1 (0.44) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |