Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7414349 | 0.83 | KDM4E (0.56) | MAPTTDP1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL804182 | 0.83 | TDP1 (0.63) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 | |
| Hydrochloric Acid SCHEMBL28308406 | 0.81 | TDP1 (0.61) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL996544 | 0.80 | TDP1 (0.64) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL3666709 | 0.79 | TDP1 (0.53) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL2323126 | 0.78 | TDP1 (0.57) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL18301478 | 0.77 | TDP1 (0.55) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL12245197 | 0.77 | TDP1 (0.55) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL30093166 | 0.77 | KDM4E (0.64) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 | |
| SCHEMBL6051881 | 0.77 | TDP1 (0.60) | MAPTTDP1SMN1; SMN2LIN28AKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1112125-A | Acyloxyhexanoic acid derivatives | CIBA GEIGY AG (CH) | 1995-11-22 | — | — | CN | claimed |
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |