SCHEMBL8894720

SCHEMBL8894720

ONc1ccc(Br)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8410091 0.83 IDO1 (0.67)
SCHEMBL17223076 0.73 CYP2A6 (0.57)
SCHEMBL409605 0.73 CYP2A6 (0.57)
SCHEMBL16526973 0.73 CYP2A6 (0.57)
SCHEMBL13148721 0.73 CYP2A6 (0.57)
SCHEMBL3388548 0.73 IDO1 (0.56)
SCHEMBL1187788 0.71
SCHEMBL602301 0.71
SCHEMBL5443582 0.71 MAOA (0.69)
SCHEMBL18508 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304507-A Synthesis method of N-substituted aryl formamide 兰州石化职业技术大学 2022-11-08 CN claimed
EP-4737448-A1 SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF Artivila (ShenZhen) Innovation Center, Ltd. (CN) 2026-05-06 EP disclosed
WO-2025002030-A1 SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF 科辉智药(深圳)新药研究中心有限公司 2025-01-02 WO disclosed
CN-119219603-A Inhibitors of SARM1 enzyme activity and uses thereof 科辉智药(深圳)新药研究中心有限公司 2024-12-31 CN disclosed
CN-118558331-A Application of ferric oxide-ferric sulfide compound as catalyst in preparation of aryl hydroxylamine by catalyzing aryl nitro compound 兰州大学 2024-08-30 CN disclosed
CN-114426510-B Synthesis method of fully substituted beta-lactam 常州大学 2024-01-23 CN disclosed
US-11724982-B2 Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-08-15 US disclosed
US-11724982-B2 Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-08-15 US disclosed
US-11724982-B2 Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-08-15 US disclosed
CN-115304507-A Synthesis method of N-substituted aryl formamide 兰州石化职业技术大学 2022-11-08 CN disclosed
US-5616563-A ANTITUMOR AGENTS UNIVERSITY OF MARYLAND BALTIMORE CAMPUS (US) 1997-04-01 US disclosed
WO-1996000061-A1 GLUTATHIONE N-HYDROXYCARBAMOYL THIOESTERS AND METHOD OF INHIBITING NEOPLASTIC GROWTH UNIVERSITY OF MARYLAND BALTIMORE COUNTY (US) 1996-01-04 WO disclosed
EP-0085596-B1 APPLICATION AS PLANT GROWTH FACTORS OF O-PHENYL HYDROXYL AMINE AND CERTAIN DERIVATIVES THEROF ROUSSEL-UCLAF (FR) 1985-03-27 EP disclosed
EP-0085596-A1 Application as plant growth factors of O-phenyl hydroxyl amine and certain derivatives therof ROUSSEL-UCLAF (FR) 1983-08-10 EP disclosed
WO-1983002545-A1 APPLICATION AS GROWTH FACTORS OF VEGETABLES OF HYDROXYLAMINE DERIVATIVES ROUSSEL UCLAF (FR) 1983-08-04 WO disclosed
US-4224340-A Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds WILLIAM H. RORER, INC. (US) 1980-09-23 US disclosed
US-4214003-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1980-07-22 US disclosed
US-4197314-A WITH A DIPHENYL NITRONE WILLIAM H. RORER, INC. (US) 1980-04-08 US disclosed
US-4153722-A ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE WILLIAM H. RORER, INC. (US) 1979-05-08 US disclosed
US-3982922-A Herbicidal compositions containing furancarboxamides VELSICOL CHEMICAL CORPORATION (US) 1976-09-28 US disclosed