SCHEMBL409605

SCHEMBL409605

Brc1ccc(Nc2ccc(Br)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.57
RAPGEF4 Q8WZA2 1/20 0.52
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 2/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
MAPK1 P28482 1/20 0.50
PTGS2 P35354 1/20 0.50
HTR2B P41595 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
APP P05067 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
MAPT P10636 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13148721 1.00 CYP2A6 (0.57) CYP2A6RAPGEF4HSD17B10ALDH1A1ALOX15
SCHEMBL16526973 1.00 CYP2A6 (0.57) CYP2A6RAPGEF4HSD17B10ALDH1A1ALOX15
SCHEMBL14942254 0.91 ALDH1A1 (0.52) CYP2A6RAPGEF4HSD17B10ALDH1A1ALOX15
SCHEMBL490926 0.88 ALDH1A1 (0.72) HSD17B10ALDH1A1ALOX15TSHRALOX12
SCHEMBL25354895 0.86 MEN1 (0.59) CYP2A6RAPGEF4ALDH1A1ALOX12MAPK1
SCHEMBL4873588 0.86 ALDH1A1 (0.68) CYP2A6RAPGEF4ALDH1A1TDP1L3MBTL1
SCHEMBL20015551 0.86 RAPGEF4 (0.43) CYP2A6RAPGEF4HSD17B10ALDH1A1ALOX15
SCHEMBL11879811 0.86 ALOX15 (0.68) CYP2A6RAPGEF4HSD17B10ALDH1A1ALOX15
SCHEMBL3800291 0.86 ALDH1A1 (0.68) CYP2A6RAPGEF4HSD17B10ALDH1A1ALOX15
SCHEMBL5543171 0.84 RAPGEF4 (0.42) CYP2A6RAPGEF4HSD17B10ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492190-B2 Polydentate organic ligand, metallo-supramolecular polymer, polymer film and preparation method thereof JILIN UNIVERSITY (CN) 2025-12-09 US claimed
US-20250236606-A1 POLYDENTATE ORGANIC LIGAND, METALLO-SUPRAMOLECULAR POLYMER, POLYMER FILM AND PREPARATION METHOD THEREOF JILIN UNIVERSITY (CN) 2025-07-24 US claimed
CN-118978510-A Preparation method, product and application of polydentate organic ligand and transition metal coordination polymer thereof 吉林大学 2024-11-19 CN claimed
CN-118091444-A Method for rapidly detecting thermal history of lithium ion battery and application 北京化工大学 2024-05-28 CN claimed
CN-116589449-B Multi-tooth organic ligand, metal supermolecular polymer, polymer film and preparation method 吉林大学 2024-05-24 CN claimed
CN-112521418-B Sulfhydryl-containing phosphorus-containing flame retardant and preparation method and application thereof 广东广山新材料股份有限公司 2024-04-30 CN claimed
US-11969719-B2 Polydentate organic ligand, preparation method and application thereof, metallo-supramolecular polymer and preparation method thereof JILIN UNIVERSITY (CN) 2024-04-30 US claimed
CN-115322376-B Method for improving conductivity of polysulfone polymer 宁夏清研高分子新材料有限公司 2024-01-30 CN claimed
CN-117362294-A Polyquinoline acridine diketone macrocyclic derivative and preparation method and application thereof 广东工业大学 2024-01-09 CN claimed
US-20230405567-A1 POLYDENTATE ORGANIC LIGAND, PREPARATION METHOD AND APPLICATION THEREOF, METALLO-SUPRAMOLECULAR POLYMER AND PREPARATION METHOD THEREOF JILIN UNIVERSITY (CN) 2023-12-21 US claimed
CN-114230581-B Multidentate organic ligand, preparation method and application thereof, metal supramolecular polymer and preparation method thereof 吉林大学 2023-01-31 CN claimed
CN-115322376-A Method for improving conductivity of polysulfone polymer 宁夏清研高分子新材料有限公司 2022-11-11 CN claimed
CN-115286517-A Diamine monomer and thermoplastic polyimide synthesized from same 慧迈材料科技(广东)有限公司 2022-11-04 CN claimed
CN-114230581-A Multidentate organic ligand, preparation method and application thereof, metal supramolecular polymer and preparation method thereof 吉林大学 2022-03-25 CN claimed
CN-109096426-B Main polymer material and preparation method and application thereof 华南协同创新研究院 2021-03-16 CN claimed
CN-110372739-A A kind of trimethylsilyl closes the preparation method of object 上海应用技术大学 2019-10-25 CN claimed
CN-109096426-A Main polymer material and preparation method and application thereof 华南协同创新研究院 2018-12-28 CN claimed
WO-2018217538-A1 SYNTHESIS OF SUBSTITUTED ACRIDINES UNIVERSITY OF ST. THOMAS (US) 2018-11-29 WO claimed
CN-104592498-B A kind of compound and its preparation method and application can detect a variety of amine steams 上海新微科技发展有限公司 2018-07-31 CN claimed
CN-101747286-A Nano-aperture 30-element triphenylamine rigid macrocyclic compound and preparation method thereof UNIV NANJING INF SCI & TECH 2010-06-23 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492190-B2 Polydentate organic ligand, metallo-supramolecular polymer, polymer film and preparation method thereof PARG, TET3, TPR CYP2A6 4345/4885RAPGEF4 1602/4885HSD17B10 4771/4885
US-20250236606-A1 POLYDENTATE ORGANIC LIGAND, METALLO-SUPRAMOLECULAR POLYMER, POLYMER FILM AND PREPARATION METHOD THEREOF PARG, TET3, TPR CYP2A6 4345/4885RAPGEF4 1602/4885HSD17B10 4771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.