Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 5/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896242 | 0.98 | EPHX1 (0.45) | EPHX1SMN1; SMN2HPGDLMNANAAA | |
| SCHEMBL8893233 | 0.83 | EPHX1 (0.59) | EPHX1SMN1; SMN2NAAAASAH1FKBP1A | |
| SCHEMBL8395658 | 0.80 | EPHX1 (0.43) | EPHX1SMN1; SMN2HPGDLMNANAAA | |
| SCHEMBL8395653 | 0.80 | EPHX1 (0.43) | EPHX1SMN1; SMN2HPGDLMNANAAA | |
| SCHEMBL696981 | 0.79 | EPHX1 (0.40) | EPHX1SMN1; SMN2HPGDLMNANAAA | |
| SCHEMBL8896994 | 0.79 | SMN1; SMN2 (0.43) | EPHX1SMN1; SMN2HPGDLMNANAAA | |
| SCHEMBL8391420 | 0.78 | EPHX1 (0.46) | EPHX1SMN1; SMN2HPGDLMNANAAA | |
| SCHEMBL8391120 | 0.78 | EPHX1 (0.46) | EPHX1SMN1; SMN2HPGDLMNANAAA | |
| SCHEMBL8391122 | 0.78 | EPHX1 (0.46) | EPHX1SMN1; SMN2HPGDLMNANAAA | |
| SCHEMBL8393778 | 0.78 | EPHX1 (0.42) | EPHX1SMN1; SMN2HPGDLMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |