(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL8894823

C=C(CC(C)N(C)C)C(=O)O.ClCc1ccccc1

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 3/20 0.41
CHRNB4 P30926 3/20 0.41
CHRNA3 P32297 3/20 0.41
CHRNA4 P43681 3/20 0.41
HPGD P15428 1/20 0.40
GRIN2D O15399 2/20 0.38
GRIN1 Q05586 2/20 0.38
GRIN2A Q12879 2/20 0.38
GRIN2B Q13224 2/20 0.38
GRIN2C Q14957 2/20 0.38
OPRM1 P35372 2/20 0.38
OPRK1 P41145 2/20 0.38
KCNH2 Q12809 2/20 0.38
CACNA1F O60840 1/20 0.38
ABCB1 P08183 1/20 0.38
CYP2B6 P20813 1/20 0.38
DRD4 P21917 1/20 0.38
DRD3 P35462 1/20 0.38
OPRD1 P41143 1/20 0.38
CACNA1D Q01668 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4383958 0.80 TET2 (0.46) CHRNB2CHRNB4CHRNA3CHRNA4
(Chloromethyl)Benzene SCHEMBL130257 0.80 HPGD (0.43) CHRNB2CHRNB4CHRNA3CHRNA4HPGD
(Chloromethyl)Benzene SCHEMBL28164357 0.79 HPGD (0.42) CHRNB2CHRNB4CHRNA3CHRNA4HPGD
(Chloromethyl)Benzene SCHEMBL28396268 0.79 HPGD (0.42) CHRNB2CHRNB4CHRNA3CHRNA4HPGD
Hydrochloric Acid SCHEMBL28385647 0.79 TET2 (0.45) CHRNB2CHRNB4CHRNA3CHRNA4
(Chloromethyl)Benzene SCHEMBL130258 0.76 UBE2N (0.44) EGFRMEN1KMT2ANPC1RAB9A
(Chloromethyl)Benzene SCHEMBL28164356 0.75 UBE2N (0.43) EGFRMEN1KMT2ANPC1RAB9A
(Chloromethyl)Benzene SCHEMBL8973203 0.74 NPC1 (0.41) HPGDEGFRALDH1A1LMNASMN1; SMN2
(Chloromethyl)Benzene SCHEMBL8894817 0.73 ALDH1A1 (0.40) HPGDEGFRALDH1A1LMNAMEN1
(Chloromethyl)Benzene SCHEMBL9245547 0.73 TRPA1 (0.44) HPGDOPRM1OPRK1KCNH2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5603841-A COPOLYMER CONTAINING DIALLYLDIMETHYLAMMONIUM CHLORIDE NALCO CHEMICAL COMPANY (US) 1997-02-18 US disclosed