Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tiaramide SCHEMBL25172 | 0.89 | NPY5R (0.58) | TMEM97NPY5RGAATSHRNPSR1 | |
| Tiaramide SCHEMBL29376518 | 0.89 | NPY5R (0.58) | TMEM97NPY5RGAATSHRNPSR1 | |
| SCHEMBL13696444 | 0.88 | NPY5R (0.61) | TMEM97NPY5RGAATSHRNPSR1 | |
| Tiaramide SCHEMBL29379184 | 0.88 | NPY5R (0.58) | TMEM97NPY5RGAATSHRNPSR1 | |
| Tiaramide SCHEMBL181916 | 0.88 | NPY5R (0.58) | TMEM97NPY5RGAATSHRNPSR1 | |
| SCHEMBL11408981 | 0.84 | NPY5R (0.57) | TMEM97NPY5RGAATSHRNPSR1 | |
| SCHEMBL8902235 | 0.84 | NPY5R (0.56) | TMEM97NPY5RGAATSHRNPSR1 | |
| SCHEMBL10547671 | 0.83 | NPY5R (0.61) | TMEM97NPY5RGAATSHRNPSR1 | |
| SCHEMBL11403158 | 0.83 | NPY5R (0.52) | TMEM97NPY5RGAATSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL10545744 | 0.82 | NPY5R (0.60) | TMEM97NPY5RGAATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043282-A2 | BENZOTHIAZOLINONES AS ANTI-ASTHMATIC AGENTS | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |