Tiaramide

Tiaramide

SCHEMBL25172

O=C(Cn1c(=O)sc2ccc(Cl)cc21)N1CCN(CCO)CC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 16/20 0.58
TMEM97 Q5BJF2 3/20 0.58
GAA P10253 1/20 0.55
TSHR P16473 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tiaramide SCHEMBL29376518 1.00 NPY5R (0.58) NPY5RTMEM97GAATSHRNPSR1
Tiaramide SCHEMBL29379184 0.99 NPY5R (0.58) NPY5RTMEM97GAATSHRNPSR1
Tiaramide SCHEMBL181916 0.99 NPY5R (0.58) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL13696444 0.90 NPY5R (0.61) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL8894950 0.89 TMEM97 (0.58) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL11308376 0.88 TMEM97 (0.57) NPY5RTMEM97TSHR
SCHEMBL11406400 0.88 NPY5R (0.47) NPY5RTMEM97
SCHEMBL11440143 0.88 TMEM97 (0.47) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL11408981 0.86 NPY5R (0.57) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL8902235 0.86 NPY5R (0.56) NPY5RTMEM97GAATSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5348 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12226549-B2 Synergistically cooperative compositions useful for soft tissue augmentation, drug delivery and related fields ALTERGON S.A. (CH) 2025-02-18 US claimed
WO-2024105529-A1 CHEMICAL DISBUDDING OF LIVESTOCK MASSEY UNIVERSITY (NZ) 2024-05-23 WO claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
EP-3829643-B1 SYNERGISTICALLY COOPERATIVE COMPOSITIONS USEFUL FOR SOFT TISSUE AUGMENTATION, DRUG DELIVERY AND RELATED FIELDS ALTERGON SA (CH) 2023-08-30 EP claimed
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 EP claimed
EP-3998932-A1 ALKALIZATION OF URINARY BLADDER WALL PRIOR TO TREATMENT WITH INTRAVESICAL HEPARIN AND ALKALINIZED LIDOCAINE TO ENHANCE RELIEF OF BLADDER PAIN SYMPTOMS Parsons, C. Lowell (US) 2022-05-25 EP claimed
US-20220118155-A1 SYNERGISTICALLY COOPERATIVE COMPOSITIONS USEFUL FOR SOFT TISSUE AUGMENTATION, DRUG DELIVERY AND RELATED FIELDS ALTERGON S.A. (CH) 2022-04-21 US claimed
US-20220096498-A1 INJECTABLE SUSTAINED-RELEASE FORMULATIONS FOR TREATMENT OF JOINT PAIN AND INFLAMMATION FORDOZ PHARMA CORP. (US) 2022-03-31 US claimed
US-11219650-B2 Agent for preventing or treating small intestinal injury induced by specific NSAID and PPI BIOFERMIN PHARMACEUTICAL CO., LTD. (JP) 2022-01-11 US claimed
CN-113795246-A Injectable sustained release formulation for the treatment of joint pain and inflammation 福多兹制药公司 2021-12-14 CN claimed
WO-1996024336-A1 NSAID NANOPARTICLES NANOSYSTEMS L.L.C. (US) 1996-08-15 WO claimed
WO-1996024339-A1 COMPOSITIONS COMPRISING NANOPARTICLES OF NSAID NANOSYSTEMS L.L.C. (US) 1996-08-15 WO claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
US-5518738-A NONSTEROIDAL ANTIINFLAMMATORY AGENTS, REDUCED GASTRIC IRRITATION NANOSYSTEM L.L.C. (US) 1996-05-21 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
EP-0644755-A1 SURFACE MODIFIED NSAID NANOPARTICLES. EASTMAN KODAK CO (US) 1995-03-29 EP claimed
EP-0341745-B1 Crosslinked carboxy polysaccharides FIDIA SPA (IT) 1994-12-14 EP claimed
WO-1993025190-A1 SURFACE MODIFIED NSAID NANOPARTICLES EASTMAN KODAK COMPANY (US) 1993-12-23 WO claimed
US-4428951-A TIARAMIDE IN WATER-INSOLUBLE OIL OR WAX FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-01-31 US claimed