Tiaramide

Tiaramide

SCHEMBL29376518

O=C(Cn1c(=O)sc2ccc(Cl)cc21)N1CCN(CCO)CC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ NPY5R Q15761 16/20 0.58
▸ TMEM97 Q5BJF2 3/20 0.58
▸ GAA P10253 1/20 0.55
▸ TSHR P16473 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tiaramide SCHEMBL25172 1.00 NPY5R (0.58) NPY5RTMEM97GAATSHRNPSR1
Tiaramide SCHEMBL181916 0.99 NPY5R (0.58) NPY5RTMEM97GAATSHRNPSR1
Tiaramide SCHEMBL29379184 0.99 NPY5R (0.58) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL13696444 0.90 NPY5R (0.61) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL8894950 0.89 TMEM97 (0.58) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL11308376 0.88 TMEM97 (0.57) NPY5RTMEM97TSHR
SCHEMBL11440143 0.88 TMEM97 (0.47) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL11406400 0.88 NPY5R (0.47) NPY5RTMEM97
SCHEMBL11408981 0.86 NPY5R (0.57) NPY5RTMEM97GAATSHRNPSR1
SCHEMBL8902235 0.86 NPY5R (0.56) NPY5RTMEM97GAATSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126138-B1 AEROSOL DELIVERY OF AT LEAST TWO LIQUID COMPOSITIONS INVOX BELGIUM NV (BE) 2024-10-16 — — EP claimed
EP-3829643-B1 SYNERGISTICALLY COOPERATIVE COMPOSITIONS USEFUL FOR SOFT TISSUE AUGMENTATION, DRUG DELIVERY AND RELATED FIELDS ALTERGON SA (CH) 2023-08-30 — — EP claimed
EP-4126138-A1 AEROSOL DELIVERY OF AT LEAST TWO LIQUID COMPOSITIONS Softhale NV (BE) 2023-02-08 — — EP claimed
EP-1931320-B1 MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE PRINCIPLE AND ORAL DOSAGE FORM COMPRISING THE SAME FLAMEL IRELAND LTD (IE) 2022-06-15 — — EP claimed
US-12629484-B2 High pressure inhalation device INVOX BELGIUM NV (BE) 2026-05-19 — — US disclosed
US-12576218-B2 Valve INVOX BELGIUM NV (BE) 2026-03-17 — — US disclosed
US-12569629-B2 Inhalation device system INVOX BELGIUM NV (BE) 2026-03-10 — — US disclosed
EP-4275725-B1 IMPROVED INHALATION DEVICE INVOX BELGIUM NV (BE) 2025-12-10 — — EP disclosed
US-12478748-B2 Aerosol delivery of at least two liquid compositions INVOX BELGIUM NV (BE) 2025-11-25 — — US disclosed
EP-4633823-A1 MICROSTRUCTURED NOZZLE invoX Belgium NV (BE) 2025-10-22 — — EP disclosed
US-20250152860-A1 INHALATION DEVICE INVOX BELGIUM NV (BE) 2025-05-15 — — US disclosed
CN-119896780-A Improved valve 索芙特海尔公司 2025-04-29 — — CN disclosed
EP-4126134-A1 INHALATION DEVICE SYSTEM Softhale NV (BE) 2023-02-08 — — EP disclosed
EP-4126138-A1 AEROSOL DELIVERY OF AT LEAST TWO LIQUID COMPOSITIONS Softhale NV (BE) 2023-02-08 — — EP disclosed
WO-2023001750-A1 INHALATION DEVICE SYSTEM WITH A COUNTING AND BLOCKING ASSEMBLY SOFTHALE NV (BE) 2023-01-26 — — WO disclosed
CN-115485000-A Aerosol delivery of at least two liquid compositions 索芙特海尔公司 2022-12-16 — — CN disclosed
CN-115087665-A Engineered platelets for targeted delivery of therapeutic agents JPV01有限公司 2022-09-20 — — CN disclosed
US-20220143328-A1 IMPROVED VALVE INVOX BELGIUM NV (BE) 2022-05-12 — — US disclosed
CN-114072388-A Plant growth regulator and method for promoting plant growth 株式会社吴羽 2022-02-18 — — CN disclosed
US-20220031969-A1 RESERVOIR FOR AN INHALATION DEVICE SOFTHALE NV (BE) 2022-02-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629484-B2 High pressure inhalation device PSMD3, PSMC2, PSMD2 NPY5R 1440/4885TMEM97 324/4885GAA 4721/4885
US-12569629-B2 Inhalation device system VMA21, CRH, AVPR2 NPY5R 532/4885TMEM97 337/4885GAA 2451/4885
US-12576218-B2 Valve PSMD9, ATP6V0C, TMCO1 NPY5R 4091/4885TMEM97 200/4885GAA 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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