Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | CASP3 | P42574 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 1/20 | 0.72 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.72 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.72 |
| ▸ | DPP4 | P27487 | 1/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896277 | 0.95 | TDP1 (0.79) | MAPTRXFP1TDP1NPC1CASP3 | |
| SCHEMBL27463271 | 0.90 | DPP4 (0.81) | MAPTRXFP1TDP1NPC1CASP3 | |
| SCHEMBL7829240 | 0.90 | DPP4 (0.65) | MAPTRXFP1TDP1NPC1CASP3 | |
| SCHEMBL7822245 | 0.88 | HSD17B10 (0.68) | MAPTRXFP1TDP1NPC1CASP3 | |
| SCHEMBL7426101 | 0.88 | TDP1 (0.85) | MAPTRXFP1TDP1NPC1CASP3 | |
| SCHEMBL9242650 | 0.88 | TDP1 (0.85) | MAPTRXFP1TDP1NPC1CASP3 | |
| SCHEMBL8559822 | 0.88 | TDP1 (0.85) | MAPTRXFP1TDP1NPC1CASP3 | |
| SCHEMBL3070677 | 0.86 | TDP1 (0.89) | MAPTRXFP1TDP1NPC1CASP3 | |
| SCHEMBL770290 | 0.86 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC3HDAC4 | |
| SCHEMBL503837 | 0.86 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |