SCHEMBL770290

SCHEMBL770290

O=C(O)CCCCCCCCCCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 1.00
RXFP1 Q9HBX9 1/20 1.00
HDAC1 Q13547 2/20 0.83
HDAC2 Q92769 2/20 0.83
HDAC3 O15379 1/20 0.83
MAPK1 P28482 1/20 0.83
ADRA1A P35348 1/20 0.83
HDAC4 P56524 1/20 0.83
SLC6A3 Q01959 1/20 0.83
SMN1; SMN2 Q16637 1/20 0.83
HDAC7 Q8WUI4 1/20 0.83
HDAC10 Q969S8 1/20 0.83
HDAC11 Q96DB2 1/20 0.83
HDAC8 Q9BY41 1/20 0.83
HDAC6 Q9UBN7 1/20 0.83
HDAC9 Q9UKV0 1/20 0.83
HDAC5 Q9UQL6 1/20 0.83
KEAP1 Q14145 1/20 0.68
ALOX5 P09917 1/20 0.67
KDM4A O75164 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2552651 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
Phenylheptanoic Acid SCHEMBL535246 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL5955839 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL1008045 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL503837 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL2554345 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL2555645 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL1008757 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL2553009 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL2551105 1.00 MAPT (1.00) MAPTRXFP1HDAC1HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105006329-B A kind of multiferroic liquid and preparation method thereof 重庆科技学院 2018-02-02 CN claimed
CN-105097177-A Multiferroic liquid and preparation method thereof UNIV CHONGQING SCI & TECH 2015-11-25 CN claimed
CN-105016396-A Multiferroic liquid and preparation method thereof UNIV CHONGQING SCI & TECH 2015-11-04 CN claimed
CN-105023692-A Multiferroic liquid and preparation method thereof UNIV CHONGQING SCI & TECH 2015-11-04 CN claimed
CN-105006329-A Multiferroic liquid and preparation method thereof UNIV CHONGQING SCI & TECH 2015-10-28 CN claimed
WO-2011124228-A1 A BIOCIDAL POLYOLEFIN YARN WITH 3-12 FILAMENTS VESTERGAARD FRANDSEN SA (CH) 2011-10-13 WO claimed
WO-2011124227-A1 BIOCIDAL ACID-ADJUSTED POLYMER WITH POLYPROPYLENE VESTERGAARD FRANDSEN SA (CH) 2011-10-13 WO claimed
EP-2086318-A2 NEUROPROTECTIVE COMPOSITIONS AND METHODS Burnham Institute for Medical Research (US) 2009-08-12 EP claimed
US-20090042980-A1 Neuroprotective compositions and methods BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2009-02-12 US claimed
WO-2008108825-A2 NEUROPROTECTIVE COMPOSITIONS AND METHODS BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2008-09-12 WO claimed
JP-2004501992-A 2004-01-22 JP claimed
CN-1437620-A Process for forming solid pressure sensitive adhesive polymer microspheres SOLUTIA INC (US) 2003-08-20 CN claimed
EP-1297033-A1 PROCESS FOR FORMING SOLID PRESSURE SENSITIVE ADHESIVE POLYMER MICROSPHERES Solutia Inc. (US) 2003-04-02 EP claimed
US-20020019482-A1 Process for forming solid pressure sensitive adhesive polymer microspheres CYTEC SURFACE SPECIALTIES, INC. 2002-02-14 US claimed
WO-2002000742-A1 PROCESS FOR FORMING SOLID PRESSURE SENSITIVE ADHESIVE POLYMER MICROSPHERES SOLUTIA, INC. (US) 2002-01-03 WO claimed
EP-0863923-B1 METHODS OF PREPARING HOLLOW ACRYLATE POLYMER MICROSPHERES MINNESOTA MINING & MFG (US) 2000-01-05 EP claimed
WO-1999029640-A2 COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF FIBROBLAST GROWTH FACTOR EISAI CO., LTD. (JP) 1999-06-17 WO claimed
EP-0863923-A1 METHODS OF PREPARING HOLLOW ACRYLATE POLYMER MICROSPHERES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-09-16 EP claimed
WO-1997020870-A1 METHODS OF PREPARING HOLLOW ACRYLATE POLYMER MICROSPHERES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-06-12 WO claimed
US-5578650-A POLYMERIZING DROPS OF ALKYL ACRYLATE IN AN AQUEOUS ACIDIFIED EMULSION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-11-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042980-A1 Neuroprotective compositions and methods KEAP1, NFE2L2, NQO1 MAPT 506/4885RXFP1 3992/4885HDAC1 585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.