SCHEMBL8894988

SCHEMBL8894988

Cc1c(OP(=O)(O)O)cc2c(c1C)OC(C)(CCCC(C)CCCC(C)CCCC(C)C)CC2

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTO1 P78417 2/20 0.71
AKT1 P31749 8/20 0.68
PDPK1 O15530 2/20 0.61
PHLPP1 O60346 2/20 0.61
ILK Q13418 2/20 0.61
LMNA P02545 3/20 0.60
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
PDE4A P27815 1/20 0.56
PDE3A Q14432 1/20 0.56
PSEN1 P49768 2/20 0.55
MAPT P10636 2/20 0.54
GSTP1 P09211 1/20 0.54
TTPA P49638 1/20 0.54
USP2 O75604 1/20 0.54
THRB P10828 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
PTPN1 P18031 1/20 0.52
NR1I2 O75469 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8652036 0.93 GSTO1 (0.64) GSTO1AKT1PDPK1PHLPP1ILK
SCHEMBL8893557 0.90 AKT1 (0.68) GSTO1AKT1PDPK1PHLPP1ILK
SCHEMBL4259671 0.86 AKT1 (0.91) GSTO1AKT1PDPK1PHLPP1ILK
SCHEMBL20917306 0.86 GSTO1 (0.73) GSTO1AKT1LMNAMEN1KMT2A
SCHEMBL708419 0.85 MEN1 (0.71) GSTO1AKT1PDPK1PHLPP1ILK
SCHEMBL29390266 0.85 MEN1 (0.71) GSTO1AKT1PDPK1PHLPP1ILK
Gamma-Tocopherol SCHEMBL8894990 0.85 AKT1 (0.82) GSTO1AKT1PDPK1PHLPP1ILK
Gamma-Tocopherol SCHEMBL27730430 0.85 AKT1 (0.82) GSTO1AKT1PDPK1PHLPP1ILK
Gamma-Tocopherol SCHEMBL8652038 0.85 AKT1 (0.82) GSTO1AKT1PDPK1PHLPP1ILK
SCHEMBL20635554 0.85 AKT1 (0.60) GSTO1AKT1PDPK1PHLPP1ILK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116600815-A Autophagy activators 株式会社力森诺科 2023-08-15 CN disclosed
CN-116507314-A Autophagy activators 株式会社力森诺科 2023-07-28 CN disclosed
CN-116322705-A Autophagy activators 株式会社力森诺科 2023-06-23 CN disclosed
CN-113825544-A Cancer cell growth inhibitor and composition for inhibiting cancer cell growth 昭和电工株式会社 2021-12-21 CN disclosed
CN-113811361-A Protective agent against atmospheric pollutants and protective composition against atmospheric pollutants 昭和电工株式会社 2021-12-17 CN disclosed
CN-112912060-A Oil-in-water droplet type external preparation for skin 昭和电工株式会社 2021-06-04 CN disclosed
CN-111182888-A Gel composition 昭和电工株式会社 2020-05-19 CN disclosed
CN-106572957-B Skin color improving agent and composition for improving skin color 昭和电工株式会社 2020-03-27 CN disclosed
WO-2019077268-A1 COSMETIC COMPOSITION FOR ACTIVE PREVENTION OF THE SIGNS OF AGEING L V M H RECHERCHE (FR) 2019-04-25 WO disclosed
WO-2015092227-A1 USE OF TOCOPHEROL PHOSPHATE AS A HYDRATING AGENT LVMH RECHERCHE (FR) 2015-06-25 WO disclosed
US-5643597-A FREE RADICAL SCAVENGERS LVMH RECHERCHE (FR) 1997-07-01 US disclosed
US-5603949-A ANTIALLERGENS; SKIN DISORDERS LVMH RECHERCHE (FR) 1997-02-18 US disclosed