Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 7/20 | 0.60 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.55 |
| ▸ | PHLPP1 | O60346 | 2/20 | 0.55 |
| ▸ | ILK | Q13418 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | TTPA | P49638 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635558 | 0.90 | AKT1 (0.57) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL708743 | 0.88 | GSTO1 (0.74) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL20635626 | 0.87 | LMNA (0.60) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL20635617 | 0.86 | GSTO1 (0.77) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL708419 | 0.86 | MEN1 (0.71) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL29390266 | 0.86 | MEN1 (0.71) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL8894988 | 0.85 | GSTO1 (0.71) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL14359795 | 0.85 | AKT1 (0.60) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL29959827 | 0.84 | AKT1 (0.64) | AKT1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL20634804 | 0.82 | GSTO1 (0.57) | AKT1GSTO1PTPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027148-A1 | MULTIFUNCTIONAL CONJUGATES | E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) | 2023-01-26 | — | — | US | disclosed |
| US-11400160-B2 | Multifunctional conjugates | E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) | 2022-08-02 | — | — | US | disclosed |
| US-20200164076-A1 | MULTIFUNCTIONAL CONJUGATES | E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) | 2020-05-28 | — | — | US | disclosed |
| WO-2019007447-A1 | MULTIFUNCTIONAL CONJUGATES | E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) | 2019-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027148-A1 | MULTIFUNCTIONAL CONJUGATES | MKI67, ACP3, CD44 | AKT1 714/4885GSTO1 148/4885PTPN1 1238/4885 |
| US-20200164076-A1 | MULTIFUNCTIONAL CONJUGATES | MKI67, ACP3, CD44 | AKT1 779/4885GSTO1 164/4885PTPN1 1198/4885 |
| US-11400160-B2 | Multifunctional conjugates | MKI67, ACP3, CD44 | AKT1 779/4885GSTO1 164/4885PTPN1 1198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.