Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 8/20 | 0.43 |
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | CTSB | P07858 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895064 | 1.00 | FOLH1 (0.46) | FOLH1CTSSCTSKCTSBCTSL | |
| SCHEMBL7434880 | 0.92 | CTSS (0.45) | CTSSCTSKCTSBCTSLKLK5 | |
| SCHEMBL7434874 | 0.92 | CTSS (0.45) | CTSSCTSKCTSBCTSLKLK5 | |
| SCHEMBL5142842 | 0.89 | KLK5 (0.47) | FOLH1CTSSCTSKCTSBCTSL | |
| SCHEMBL6305846 | 0.89 | KLK5 (0.47) | FOLH1CTSSCTSKCTSBCTSL | |
| SCHEMBL7283432 | 0.89 | KLK5 (0.47) | FOLH1CTSSCTSKCTSBCTSL | |
| SCHEMBL6446803 | 0.89 | KLK5 (0.47) | FOLH1CTSSCTSKCTSBCTSL | |
| SCHEMBL7796450 | 0.89 | KLK5 (0.47) | FOLH1CTSSCTSKCTSBCTSL | |
| SCHEMBL7398818 | 0.89 | KLK5 (0.47) | FOLH1CTSSCTSKCTSBCTSL | |
| SCHEMBL9546505 | 0.88 | NPSR1 (0.47) | CTSSCTSKCTSBCTSLKLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |