Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538501 | 0.80 | MAPT (0.52) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10576118 | 0.80 | SMN1; SMN2 (0.45) | MAPTKMT2AMEN1ALDH1A1NUDT1 | |
| SCHEMBL11170200 | 0.77 | NUDT1 (0.58) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8892697 | 0.75 | SLC6A3 (0.47) | KMT2AMEN1ALDH1A1NUDT1SLC6A3 | |
| SCHEMBL6631073 | 0.72 | HTT (0.46) | MAPTKMT2AMEN1POLBGAA | |
| SCHEMBL28534974 | 0.69 | MAPT (0.48) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10852640 | 0.69 | MAPT (0.36) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4872492 | 0.69 | MAPT (0.51) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL8892303 | 0.68 | MAPT (0.43) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL7009144 | 0.67 | NPC1 (0.40) | MAPTKMT2AALDH1A1KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |