Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | TGM2 | P21980 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | TDO2 | P48775 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13055383 | 0.91 | LMNA (0.80) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL6447301 | 0.88 | HTT (0.72) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL707687 | 0.88 | LMNA (0.71) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL18254066 | 0.87 | HTT (0.81) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL15346534 | 0.86 | HTT (0.79) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL9874334 | 0.86 | HTT (0.79) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL9340146 | 0.86 | HTT (0.79) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| Benzyl Phenethylcarbamate SCHEMBL4287199 | 0.86 | LMNA (0.73) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL375858 | 0.86 | LMNA (0.73) | LMNASMN1; SMN2HTTTGM2L3MBTL1 | |
| SCHEMBL5019074 | 0.86 | LMNA (0.73) | LMNASMN1; SMN2HTTTGM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |
| US-4461761-A | IMMUNO-REGULATORS | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1984-07-24 | — | — | US | disclosed |