Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895446 | 0.98 | MEN1 (0.46) | MEN1KMT2ATBXA2RTBXAS1NPSR1 | |
| SCHEMBL8898394 | 0.97 | MEN1 (0.45) | MEN1KMT2ATBXA2RTBXAS1NPSR1 | |
| SCHEMBL8897707 | 0.92 | NPSR1 (0.48) | TBXA2RTBXAS1NPSR1L3MBTL1UTS2R | |
| SCHEMBL8895481 | 0.92 | KMT2A (0.47) | MEN1KMT2AUTS2RMMP3MMP13 | |
| SCHEMBL8894975 | 0.91 | NPSR1 (0.47) | TBXA2RTBXAS1NPSR1L3MBTL1UTS2R | |
| SCHEMBL8895978 | 0.91 | S1PR1 (0.47) | TBXA2RTBXAS1NPSR1L3MBTL1UTS2R | |
| SCHEMBL8898267 | 0.91 | S1PR1 (0.47) | TBXA2RTBXAS1NPSR1L3MBTL1UTS2R | |
| SCHEMBL8897143 | 0.90 | KMT2A (0.45) | MEN1KMT2AUTS2RMMP3MMP13 | |
| SCHEMBL8895718 | 0.90 | ALDH1A1 (0.49) | TBXA2RTBXAS1NPSR1UTS2RMMP13 | |
| SCHEMBL8895228 | 0.89 | KMT2A (0.45) | MEN1KMT2AUTS2RMMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |