Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897143 | 0.98 | KMT2A (0.45) | KMT2AMEN1UTS2RSMN1; SMN2ALDH1A1 | |
| SCHEMBL8895228 | 0.97 | KMT2A (0.45) | KMT2AMEN1UTS2RSMN1; SMN2ALDH1A1 | |
| SCHEMBL8896098 | 0.93 | UTS2R (0.46) | KMT2AMEN1UTS2RALDH1A1CYP1A2 | |
| SCHEMBL8895435 | 0.93 | UTS2R (0.45) | KMT2AMEN1UTS2RALDH1A1CYP1A2 | |
| SCHEMBL8895299 | 0.92 | MEN1 (0.47) | KMT2AMEN1UTS2RSMN1; SMN2ALDH1A1 | |
| SCHEMBL8896463 | 0.92 | UTS2R (0.44) | KMT2AMEN1UTS2RALDH1A1CYP1A2 | |
| SCHEMBL8898667 | 0.92 | UTS2R (0.44) | KMT2AMEN1UTS2RALDH1A1CYP1A2 | |
| SCHEMBL8897066 | 0.92 | UTS2R (0.49) | KMT2AMEN1UTS2RALDH1A1CYP1A2 | |
| SCHEMBL8898580 | 0.91 | ALDH1A1 (0.49) | KMT2AMEN1UTS2RSMN1; SMN2ALDH1A1 | |
| SCHEMBL8895046 | 0.91 | UTS2R (0.47) | KMT2AMEN1UTS2RALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |