Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 11/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | C1S | P09871 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895306 | 0.77 | F7 (0.43) | WDR5NQO2ITGB3ITGA2BPRSS1 | |
| SCHEMBL8885569 | 0.77 | PRSS1 (0.53) | ITGB3ITGA2BF2PLGPRSS1 | |
| SCHEMBL8886356 | 0.73 | ITGB3 (0.59) | WDR5NQO2ITGB3ITGA2BPLAU | |
| Hydrochloric Acid SCHEMBL8887063 | 0.72 | F2 (0.44) | NQO2ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL13618604 | 0.71 | PRSS1 (0.47) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL8407326 | 0.71 | NQO2 (0.45) | WDR5NQO2ITGB3ITGA2B | |
| SCHEMBL8886144 | 0.71 | ITGB3 (0.54) | WDR5NQO2ITGB3ITGA2BPLAU | |
| Acetic Acid SCHEMBL398148 | 0.71 | NQO2 (0.72) | WDR5NQO2F2ALDH1A1 | |
| SCHEMBL9259667 | 0.70 | ITGB3 (0.39) | NQO2ITGB3ITGA2BPLAU | |
| SCHEMBL8887767 | 0.68 | ITGB3 (0.47) | WDR5NQO2ITGB3ITGA2BPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |