Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.59 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 6/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886144 | 0.92 | ITGB3 (0.54) | ITGB3ITGA2BWDR5PLAUNQO2 | |
| Hydrochloric Acid SCHEMBL8887360 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BWDR5PLAUNQO2 | |
| SCHEMBL8887767 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BWDR5PLAUNQO2 | |
| SCHEMBL27268123 | 0.79 | HSD17B10 (0.49) | ITGB3ITGA2BLMNARAB9ASMN1; SMN2 | |
| SCHEMBL7364770 | 0.74 | KMT2A (0.53) | LMNARAB9A | |
| SCHEMBL9558456 | 0.74 | ITGB3 (0.69) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8885198 | 0.74 | ITGB3 (0.47) | ITGB3ITGA2BPLAU | |
| SCHEMBL1114865 | 0.73 | DRD4 (0.50) | LMNARAB9A | |
| SCHEMBL8895301 | 0.73 | WDR5 (0.44) | ITGB3ITGA2BWDR5PLAUNQO2 | |
| SCHEMBL8886607 | 0.73 | ITGB3 (0.57) | ITGB3ITGA2BWDR5NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597825-A | AGGREGATION INHIBITORS | DR. KARL THOMAE GMBH (DE) | 1997-01-28 | — | — | US | disclosed |
| EP-0496378-B1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1995-09-20 | — | — | EP | disclosed |
| EP-0496378-A1 | Biphenylderivatives, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |