Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893058 | 0.81 | PPARA (0.38) | TSHRABCB11CYP1A2CYP3A4HTR2A | |
| SCHEMBL8892401 | 0.80 | PREP (0.43) | CYP1A2CYP3A4PPARAPREPCA12 | |
| SCHEMBL23291809 | 0.79 | ALDH1A1 (0.48) | TSHRABCB11CYP1A2CYP3A4HTR2A | |
| SCHEMBL9214790 | 0.78 | TSHR (0.36) | TSHRABCB11CYP1A2CYP3A4HTR2A | |
| SCHEMBL9290105 | 0.78 | CNR2 (0.45) | TSHRABCB11CYP1A2CYP3A4HTR2A | |
| SCHEMBL7308998 | 0.78 | CA12 (0.53) | TSHRCYP1A2CYP3A4CA12CA1 | |
| SCHEMBL8893037 | 0.77 | ESR1 (0.50) | TSHRABCB11CYP1A2CYP3A4HTR2A | |
| SCHEMBL11839741 | 0.77 | ALDH1A1 (0.49) | TSHRABCB11CYP1A2CYP3A4HTR2A | |
| SCHEMBL14653829 | 0.77 | POLB (0.52) | TSHRABCB11CYP1A2CYP3A4HTR2A | |
| SCHEMBL7756224 | 0.77 | NPC1 (0.52) | TSHRABCB11CYP1A2CYP3A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038997-A1 | SUBSTITUTED OXAZOLIDINEDIONES AND THEIR USE AS FUNGICIDES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |
| EP-0630370-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993022299-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |
| WO-1993018016-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-16 | — | — | WO | disclosed |