Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893423 | 0.85 | NR1H2 (0.38) | PPARATSHRPPARGNR1H2NR1H3 | |
| SCHEMBL8895342 | 0.81 | TSHR (0.41) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL8893779 | 0.78 | PIN1 (0.38) | PPARATSHRPPARGPIN1ALDH1A1 | |
| SCHEMBL9214790 | 0.77 | TSHR (0.36) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL9290105 | 0.74 | CNR2 (0.45) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL8893037 | 0.73 | ESR1 (0.50) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL11839741 | 0.72 | ALDH1A1 (0.49) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL7756224 | 0.72 | NPC1 (0.52) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL14653829 | 0.72 | POLB (0.52) | PPARATSHRABCB11CYP1A2CYP3A4 | |
| SCHEMBL10584058 | 0.72 | ACHE (0.37) | TSHRCYP1A2CYP3A4KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997038995-A1 | FUNGICIDAL OXAZOLIDINEDIONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |
| WO-1997038997-A1 | SUBSTITUTED OXAZOLIDINEDIONES AND THEIR USE AS FUNGICIDES | ZENECA LIMITED (GB) | 1997-10-23 | — | — | WO | disclosed |