SCHEMBL889543

CC[C@H]1O[C@@H](n2cnc3c(=O)n(C(=O)OC(C)(C)C)c(N(C(C)=O)C(=O)OC(C)(C)C)nc32)CC1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY1	P47900	1/20	0.34

▸	KDM4E	B2RXH2	1/20	0.32

▸	CYP1A2	P05177	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14789006	1.00	P2RY1 (0.34)	P2RY1KDM4ECYP1A2
SCHEMBL12570241	0.93	P2RY1 (0.36)	P2RY1KDM4E
SCHEMBL12762705	0.93	P2RY1 (0.36)	P2RY1KDM4E
SCHEMBL14789004	0.83	P2RY1 (0.36)	P2RY1KDM4ECYP1A2
SCHEMBL889697	0.83	P2RY1 (0.36)	P2RY1KDM4ECYP1A2
SCHEMBL889632	0.82	P2RX3 (0.33)	CYP1A2
SCHEMBL14789012	0.82	P2RX3 (0.33)	CYP1A2
SCHEMBL889533	0.79	HIF1A (0.38)	P2RY1
SCHEMBL12570244	0.76	P2RX3 (0.32)	P2RY1
SCHEMBL12762704	0.76	P2RX3 (0.32)	P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8361727-B2	3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing	LASERGEN, INC. (US)	2013-01-29	—	—	US	disclosed
US-20110287427-A1	3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING	LASERGEN, INC. (US)	2011-11-24	—	—	US	disclosed