SCHEMBL889632

CC[C@H]1O[C@@H](n2cnc3c(=O)n(C(=O)OC(C)(C)C)c(N(Cc4ccccc4[N+](=O)[O-])C(=O)OC(C)(C)C)nc32)CC1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	P2RX3	P56373	1/20	0.33

▸	SLC29A1	Q99808	1/20	0.32

▸	CYP1A2	P05177	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL14789012	1.00	P2RX3 (0.33)	P2RX3SLC29A1CYP1A2
SCHEMBL12570244	0.94	P2RX3 (0.32)	P2RX3SLC29A1
SCHEMBL12762704	0.94	P2RX3 (0.32)	P2RX3SLC29A1
SCHEMBL889553	0.85	SLC29A1 (0.37)	SLC29A1
SCHEMBL889543	0.82	P2RY1 (0.34)	CYP1A2
SCHEMBL14789006	0.82	P2RY1 (0.34)	CYP1A2
SCHEMBL12570159	0.79	SLC29A1 (0.36)	SLC29A1
SCHEMBL889555	0.77	SLC29A1 (0.34)	SLC29A1
SCHEMBL889701	0.77	SLC29A1 (0.34)	SLC29A1
SCHEMBL889697	0.76	P2RY1 (0.36)	CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8361727-B2	3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing	LASERGEN, INC. (US)	2013-01-29	—	—	US	disclosed
US-20110287427-A1	3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING	LASERGEN, INC. (US)	2011-11-24	—	—	US	disclosed