Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895376 | 0.98 | SIGMAR1 (0.41) | SIGMAR1NPSR1GFERFFAR1FFAR4 | |
| SCHEMBL8897514 | 0.95 | NPSR1 (0.42) | SIGMAR1NPSR1GFERFFAR1FFAR4 | |
| SCHEMBL8894981 | 0.91 | FFAR1 (0.48) | SIGMAR1NPSR1GFERFFAR1FFAR4 | |
| SCHEMBL8418078 | 0.91 | SIGMAR1 (0.39) | SIGMAR1NPSR1GFERFFAR1FFAR4 | |
| SCHEMBL8896362 | 0.90 | IDO1 (0.50) | NPSR1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8895305 | 0.90 | UTS2R (0.46) | NPSR1ALDH1A1SMN1; SMN2POLBIDO1 | |
| SCHEMBL8896101 | 0.90 | FFAR1 (0.47) | SIGMAR1NPSR1GFERFFAR1FFAR4 | |
| SCHEMBL8896727 | 0.90 | NPSR1 (0.51) | SIGMAR1NPSR1GFERFFAR1FFAR4 | |
| SCHEMBL8896944 | 0.90 | ALDH1A1 (0.44) | NPSR1ALDH1A1CA12CA7CA9 | |
| SCHEMBL8897755 | 0.89 | FFAR1 (0.47) | SIGMAR1NPSR1GFERFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |