Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079873 | 0.83 | CTNNB1 (0.39) | CTNNB1CBFBKDM4ERECQLCHEK2 | |
| SCHEMBL8894008 | 0.82 | PPARG (0.40) | CTNNB1PPARGPPARAACACBITGB3 | |
| SCHEMBL8893687 | 0.81 | CTNNB1 (0.34) | CTNNB1PPARGPPARAACACBKDM4E | |
| SCHEMBL8893598 | 0.79 | TP53 (0.37) | CTNNB1PPARGPPARAACACBCYP2C9 | |
| SCHEMBL8894060 | 0.78 | PPARG (0.38) | CTNNB1PPARGPPARAACACBCHEK2 | |
| SCHEMBL9079842 | 0.77 | CTNNB1 (0.36) | CTNNB1KDM4ERECQLCHEK2 | |
| SCHEMBL20745405 | 0.73 | CBFB (0.43) | CBFBKDM4ERECQLCHEK2 | |
| SCHEMBL9446763 | 0.72 | SLC6A4 (0.41) | PPARGPPARAACACB | |
| SCHEMBL17544106 | 0.70 | CBFB (0.46) | CBFBCHEK2 | |
| SCHEMBL9446680 | 0.70 | PPARG (0.35) | PPARGPPARAACACBESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618793-A | ANTIFUNGAL AGENT | SCHERING CORPORATION (US) | 1997-04-08 | — | — | US | disclosed |
| US-5461055-A | Fungicides | SCHERING CORPORATION (US) | 1995-10-24 | — | — | US | disclosed |
| US-5346898-A | FOR TREATING FUNGAL INFECTIONS IN MAMMALS | SCHERING CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |