Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894008 | 0.86 | PPARG (0.40) | PPARGPPARACTNNB1LNPEPITGB3 | |
| SCHEMBL8895538 | 0.78 | CTNNB1 (0.35) | PPARGPPARACTNNB1ITGB3ITGB1 | |
| SCHEMBL8893598 | 0.78 | TP53 (0.37) | PPARGPPARACTNNB1ACACBNPSR1 | |
| SCHEMBL8893687 | 0.77 | CTNNB1 (0.34) | PPARGPPARACTNNB1ACACB | |
| SCHEMBL8892975 | 0.77 | ITGB3 (0.42) | ITGB3ITGA2BELANE | |
| SCHEMBL9079873 | 0.75 | CTNNB1 (0.39) | CTNNB1F2ELANECHEK2 | |
| SCHEMBL9446763 | 0.72 | SLC6A4 (0.41) | PPARGPPARALNPEPACACB | |
| SCHEMBL9079842 | 0.72 | CTNNB1 (0.36) | CTNNB1CHEK2 | |
| SCHEMBL1712972 | 0.68 | ITGB3 (0.63) | PPARGPPARAITGB3ITGA2BACACB | |
| SCHEMBL1712530 | 0.68 | ITGB3 (0.63) | PPARGPPARAITGB3ITGA2BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618793-A | ANTIFUNGAL AGENT | SCHERING CORPORATION (US) | 1997-04-08 | — | — | US | disclosed |
| US-5461055-A | Fungicides | SCHERING CORPORATION (US) | 1995-10-24 | — | — | US | disclosed |
| US-5346898-A | FOR TREATING FUNGAL INFECTIONS IN MAMMALS | SCHERING CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |