Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894008 | 0.87 | PPARG (0.40) | PPARGPPARACTNNB1NPSR1TDP1 | |
| SCHEMBL8895538 | 0.79 | CTNNB1 (0.35) | PPARGPPARACTNNB1ACACBCYP2C9 | |
| SCHEMBL8894060 | 0.78 | PPARG (0.38) | PPARGPPARACTNNB1NPSR1TDP1 | |
| SCHEMBL8893687 | 0.78 | CTNNB1 (0.34) | TP53PPARGPPARACTNNB1ACACB | |
| SCHEMBL9079873 | 0.76 | CTNNB1 (0.39) | CTNNB1 | |
| SCHEMBL5700981 | 0.73 | LMNA (0.41) | TP53SMN1; SMN2KMT2AMEN1L3MBTL1 | |
| SCHEMBL14726814 | 0.73 | MLYCD (0.43) | PPARGKMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL9079842 | 0.73 | CTNNB1 (0.36) | CTNNB1 | |
| SCHEMBL8400523 | 0.72 | TDP1 (0.55) | SMN1; SMN2L3MBTL1LMNACTNNB1TDP1 | |
| SCHEMBL8892975 | 0.71 | ITGB3 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618793-A | ANTIFUNGAL AGENT | SCHERING CORPORATION (US) | 1997-04-08 | — | — | US | disclosed |
| US-5461055-A | Fungicides | SCHERING CORPORATION (US) | 1995-10-24 | — | — | US | disclosed |
| US-5346898-A | FOR TREATING FUNGAL INFECTIONS IN MAMMALS | SCHERING CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |