Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570981 | 0.86 | KMT2A (0.55) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL28570980 | 0.86 | KMT2A (0.55) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL18119752 | 0.84 | KMT2A (0.56) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL8895279 | 0.82 | ROCK2 (0.49) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL8895275 | 0.82 | ROCK2 (0.49) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL19232114 | 0.79 | ALDH1A1 (0.64) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL19707984 | 0.79 | KMT2A (0.66) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL19987418 | 0.78 | ALDH1A1 (0.56) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL10403114 | 0.77 | SMN1; SMN2 (0.46) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL11435364 | 0.76 | KMT2A (0.58) | KMT2ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643855-A | Herbicidal imidazolones | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1994014817-A1 | HERBICIDAL IMIDAZOLONES AND A PROCESS FOR THEIR MANUFACTURE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-07 | — | — | WO | disclosed |