SCHEMBL8895765

SCHEMBL8895765

C=CCN(CC=C)C(=O)c1ccc(OCCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LSS P48449 11/20 0.39
F2 P00734 2/20 0.39
HTT P42858 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8894477 0.98 F2 (0.40) LSSF2HTTL3MBTL1ALDH1A1
SCHEMBL8896466 0.88 LSS (0.39) LSSF2HTTL3MBTL1ALDH1A1
SCHEMBL8895854 0.86 HTT (0.38) LSSF2HTTL3MBTL1ALDH1A1
SCHEMBL8895921 0.85 LSS (0.42) LSSF2HTTL3MBTL1ALDH1A1
SCHEMBL8895029 0.85 MAOB (0.41) HTTL3MBTL1POLB
SCHEMBL8895659 0.85 THRB (0.40) HTTPOLB
SCHEMBL8894781 0.85 LSS (0.37) LSSF2HTTL3MBTL1ALDH1A1
SCHEMBL8895295 0.84 POLB (0.40) F2HTTPOLB
SCHEMBL7979429 0.83 ALDH1A1 (0.41) F2HTTALDH1A1MEN1KMT2A
SCHEMBL8896291 0.83 TSHR (0.43) HTTALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997027173-A2 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-31 WO disclosed