Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895858 | 1.00 | ESR1 (0.39) | ESR1ESR2USP30HDAC6TMEM97 | |
| SCHEMBL8562237 | 0.81 | ESR1 (0.39) | ESR1ESR2HDAC6ABHD6PDE4B | |
| SCHEMBL8562233 | 0.81 | ESR1 (0.39) | ESR1ESR2HDAC6ABHD6PDE4B | |
| SCHEMBL8567428 | 0.80 | ESR1 (0.40) | ESR1ESR2USP30HDAC6ABHD6 | |
| SCHEMBL8567424 | 0.80 | ESR1 (0.40) | ESR1ESR2USP30HDAC6ABHD6 | |
| SCHEMBL8564189 | 0.80 | ESR1 (0.41) | ESR1ESR2HDAC6TMEM97SIGMAR1 | |
| SCHEMBL8564198 | 0.80 | ESR1 (0.41) | ESR1ESR2HDAC6TMEM97SIGMAR1 | |
| SCHEMBL8562057 | 0.79 | ESR1 (0.38) | ESR1ESR2HDAC6TMEM97SIGMAR1 | |
| SCHEMBL8561418 | 0.79 | ESR1 (0.41) | ESR1ESR2HDAC6TMEM97SIGMAR1 | |
| SCHEMBL8568715 | 0.79 | F10 (0.39) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |