Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.59 |
| ▸ | IL1RN | P18510 | 8/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | GHSR | Q92847 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896690 | 1.00 | ECE1 (0.59) | ECE1IL1RNERAP2ERAP1KMT2A | |
| SCHEMBL8893523 | 0.95 | ECE1 (0.59) | ECE1IL1RNERAP2ERAP1GHSR | |
| SCHEMBL8894507 | 0.95 | ECE1 (0.59) | ECE1IL1RNERAP2ERAP1GHSR | |
| SCHEMBL8893522 | 0.95 | ECE1 (0.59) | ECE1IL1RNERAP2ERAP1GHSR | |
| SCHEMBL8892706 | 0.94 | ECE1 (0.57) | ECE1IL1RNERAP2ERAP1GHSR | |
| SCHEMBL8894510 | 0.92 | IL1RN (0.54) | ECE1IL1RNERAP2ERAP1GHSR | |
| SCHEMBL8895429 | 0.92 | IL1RN (0.54) | ECE1IL1RNERAP2ERAP1GHSR | |
| SCHEMBL8892946 | 0.92 | CTSC (0.55) | ECE1IL1RNERAP2GHSR | |
| SCHEMBL8894262 | 0.90 | ECE1 (0.60) | ECE1KMT2AMEN1GHSR | |
| SCHEMBL8896053 | 0.90 | ECE1 (0.60) | ECE1KMT2AMEN1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | claimed |
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996010037-A1 | PEPTIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |