Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | GHSR | Q92847 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894262 | 1.00 | ECE1 (0.60) | ECE1KDM4EMEN1LMNAMPO | |
| SCHEMBL8895364 | 0.96 | GHSR (0.61) | ECE1GHSR | |
| SCHEMBL8894741 | 0.96 | GHSR (0.61) | ECE1GHSR | |
| SCHEMBL8896981 | 0.96 | GHSR (0.61) | ECE1GHSR | |
| SCHEMBL8894890 | 0.95 | GHSR (0.59) | ECE1KDM4EMEN1LMNAMPO | |
| SCHEMBL8896673 | 0.92 | NPY1R (0.55) | GHSR | |
| SCHEMBL8895453 | 0.92 | NPY1R (0.55) | GHSR | |
| SCHEMBL8894656 | 0.91 | CTSC (0.57) | ECE1MEN1KMT2AACEGHSR | |
| SCHEMBL8895938 | 0.90 | ECE1 (0.59) | ECE1MEN1KMT2AGHSR | |
| SCHEMBL8896690 | 0.90 | ECE1 (0.59) | ECE1MEN1KMT2AGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | claimed |
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996010037-A1 | PEPTIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |