Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.55 |
| ▸ | CCKBR | P32239 | 3/20 | 0.54 |
| ▸ | CCKAR | P32238 | 1/20 | 0.54 |
| ▸ | IL1RN | P18510 | 4/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.52 |
| ▸ | ECE1 | P42892 | 3/20 | 0.51 |
| ▸ | NPY1R | P25929 | 3/20 | 0.49 |
| ▸ | NPY2R | P49146 | 3/20 | 0.49 |
| ▸ | NPY4R | P50391 | 3/20 | 0.49 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894358 | 0.95 | CCKBR (0.59) | CTSCCCKBRCCKARECE1GHSR | |
| SCHEMBL8892643 | 0.93 | CCKBR (0.54) | CTSCCCKBRCCKARIL1RNERAP2 | |
| SCHEMBL8894656 | 0.93 | CTSC (0.57) | CTSCCCKBRCCKARECE1NPY1R | |
| SCHEMBL8895938 | 0.92 | ECE1 (0.59) | IL1RNERAP2ECE1GHSR | |
| SCHEMBL8896690 | 0.92 | ECE1 (0.59) | IL1RNERAP2ECE1GHSR | |
| SCHEMBL8894394 | 0.89 | CCKBR (0.59) | CTSCCCKBRCCKARNPY1RNPY2R | |
| SCHEMBL8893523 | 0.88 | ECE1 (0.59) | IL1RNERAP2ECE1GHSR | |
| SCHEMBL8893522 | 0.88 | ECE1 (0.59) | IL1RNERAP2ECE1GHSR | |
| SCHEMBL8894507 | 0.88 | ECE1 (0.59) | IL1RNERAP2ECE1GHSR | |
| SCHEMBL8892706 | 0.87 | ECE1 (0.57) | IL1RNERAP2ECE1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | claimed |
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996010037-A1 | PEPTIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |