Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.72 |
| ▸ | FCER2 | P06734 | 3/20 | 0.72 |
| ▸ | MME | P08473 | 2/20 | 0.69 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.62 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.62 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.62 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP7 | P09237 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP12 | P39900 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895943 | 1.00 | MMP1 (0.72) | MMP1FCER2MMEERAP2ERAP1 | |
| SCHEMBL8899092 | 0.94 | MME (0.68) | MMP1FCER2MMEERAP2ERAP1 | |
| SCHEMBL8899095 | 0.94 | MME (0.68) | MMP1FCER2MMEERAP2ERAP1 | |
| SCHEMBL8898699 | 0.90 | MME (0.63) | MMP1FCER2MMEERAP2ERAP1 | |
| SCHEMBL8898706 | 0.90 | MME (0.63) | MMP1FCER2MMEERAP2ERAP1 | |
| SCHEMBL4226365 | 0.90 | MME (0.63) | MMP1FCER2MMEERAP2ERAP1 | |
| SCHEMBL11404202 | 0.90 | MME (0.81) | MMP1FCER2MME | |
| SCHEMBL11404199 | 0.90 | MME (0.81) | MMP1FCER2MME | |
| SCHEMBL9068522 | 0.90 | MME (0.81) | MMEMMP2MMP7MMP9MMP12 | |
| SCHEMBL9751225 | 0.90 | MME (0.81) | MMEMMP2MMP7MMP9MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686422-A | Synthetic inhibitors of mammalian collagenase | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0358660-B1 | SYNTHETIC INHIBITORS OF MAMMALIAN COLLAGENASE | RES CORP TECHNOLOGIES INC (US) | 1994-05-25 | — | — | EP | disclosed |