Sugi Predict

Sugi Predict / Compounds / SCHEMBL8895972

SCHEMBL8895972

SCHEMBL8895972

C[Si](C)(C)[Si](c1ccccc1)(c1ccccc1)[Si](c1ccccc1)(c1ccccc1)[Si](c1ccccc1)(c1ccccc1)[Si](c1ccccc1)(c1ccccc1)[Si](C)(C)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.37
▸ ESR2 Q92731 1/20 0.37
▸ NR1H2 P55055 1/20 0.31
▸ NR1H3 Q13133 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8662412 0.82 ESR1 (0.44) ESR1ESR2NR1H2NR1H3
SCHEMBL11024970 0.77 ESR1 (0.41) ESR1ESR2NR1H2NR1H3
SCHEMBL9340348 0.76 ESR1 (0.44) ESR1ESR2NR1H2NR1H3
SCHEMBL239179 0.76 ESR1 (0.48) ESR1ESR2NR1H2NR1H3
SCHEMBL23532344 0.71 ESR1 (0.44) ESR1ESR2NR1H2NR1H3
SCHEMBL11023990 0.71 ESR1 (0.44) ESR1ESR2NR1H2NR1H3
SCHEMBL244122 0.69 ESR1 (0.42) ESR1ESR2NR1H2NR1H3
SCHEMBL10150936 0.69 ESR1 (0.42) ESR1ESR2NR1H2NR1H3
SCHEMBL8415397 0.68 CA4 (0.42) ESR1ESR2
SCHEMBL8416097 0.68 ESR1 (0.38) ESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0622396-B1 Polysilanes and method for producing the same JAPAN RES DEV CORP (JP) 1997-12-03 — — EP disclosed
US-5663271-A Polysilanes and method for producing the same RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1997-09-02 — — US disclosed
EP-0622396-A2 Polysilanes and method for producing the same Research Development Corporation of Japan (JP) 1994-11-02 — — EP disclosed