Sugi Predict

Sugi Predict / Compounds / SCHEMBL244122

SCHEMBL244122

SCHEMBL244122

C[Si](C)(c1ccccc1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ESR1 P03372 1/20 0.42
▸ ESR2 Q92731 1/20 0.42
▸ NR1H2 P55055 2/20 0.34
▸ NR1H3 Q13133 2/20 0.34
▸ LMNA P02545 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ ALOX12 P18054 1/20 0.33
▸ ACHE P22303 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ KCNN4 O15554 1/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ ALDH1A1 P00352 2/20 0.30
▸ HSD17B10 Q99714 1/20 0.30
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2171513 0.88 ESR1 (0.35) ESR1ESR2
SCHEMBL239179 0.84 ESR1 (0.48) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL8384123 0.79 ESR1 (0.44) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL787696 0.79 ESR1 (0.44) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL23532344 0.79 ESR1 (0.44) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL9340348 0.79 ESR1 (0.44) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL11023990 0.79 ESR1 (0.44) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL242095 0.77 ALDH1A1 (0.40) ESR1ESR2LMNATSHRALOX12
SCHEMBL10150936 0.77 ESR1 (0.42) ESR1ESR2NR1H2NR1H3LMNA
SCHEMBL14666537 0.77 ESR1 (0.42) ESR1ESR2NR1H2NR1H3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2346815-B1 METHOD FOR PRODUCING COMPOUNDS INCLUDING NITRILE FUNCTIONS INVISTA Technologies S à r l (CH) 2016-04-20 — — EP claimed
US-9174207-B2 Process for producing compounds comprising nitrile functions INVISTA NORTH AMERICA S.A.R.L. (US) 2015-11-03 — — US claimed
US-20120004440-A1 PROCESS FOR PRODUCING COMPOUNDS COMPRISING NITRILE FUNCTIONS INVISTA NORTH AMERICA SARL 2012-01-05 — — US claimed
US-20110288327-A1 PROCESS FOR THE MANUFACTURE OF COMPOUNDS COMPRISING NITRILE FUNCTIONAL GROUPS RHODIA OPERATIONS (FR) 2011-11-24 — — US claimed
EP-2382186-A1 METHOD FOR PRODUCING COMPOUNDS INCLUDING NITRILE FUNCTIONS Rhodia Opérations (FR) 2011-11-02 — — EP claimed
WO-2010086246-A1 METHOD FOR PRODUCING COMPOUNDS INCLUDING NITRILE FUNCTIONS RHODIA OPERATIONS (FR) 2010-08-05 — — WO claimed
WO-2010046226-A1 METHOD FOR PRODUCING COMPOUNDS INCLUDING NITRILE FUNCTIONS RHODIA OPERATIONS (FR) 2010-04-29 — — WO claimed
JP-9232288-A — — None — — JP disclosed
CN-113169299-B Nonaqueous electrolyte secondary battery 三菱化学株式会社 2024-07-02 — — CN disclosed
CN-116656240-B Photo-curing coating and coating prepared based on epoxy acrylate condensed alkenyl silicone resin 云南众合硅基新材料有限公司 2024-06-07 — — CN disclosed
CN-116655921-A Photo-curing epoxy acrylate condensed alkenyl silicone resin, preparation method and application 云南众合硅基新材料有限公司 2023-08-29 — — CN disclosed
CN-116656240-A Photo-curing coating and coating prepared based on epoxy acrylate condensed alkenyl silicone resin 云南众合硅基新材料有限公司 2023-08-29 — — CN disclosed
CN-112110950-B Preparation method of disilane 杭州师范大学 2023-02-14 — — CN disclosed
WO-2010046226-A1 METHOD FOR PRODUCING COMPOUNDS INCLUDING NITRILE FUNCTIONS RHODIA OPERATIONS (FR) 2010-04-29 — — WO disclosed
US-20070260026-A1 Catalyst for Olefin Polymerization Process for Producing Olefin Polymer, Olefin Copolymer, Novel Transition Metal Compound, and Process for Producing Transition Metal Compound MITSUI CHEMICALS, INC. 2007-11-08 — — US disclosed
EP-1788002-A1 CATALYSTS FOR OLEFIN POLYMERIZATION, PROCESS FOR PRODUCTION OF OLEFIN POLYMERS, OLEFIN COPOLYMERS, NOVEL TRANSITION METAL COMPOUNDS, AND PROCESS FOR PRODUCTION OF TRANSITION METAL COMPOUNDS Mitsui Chemicals, Inc. (JP) 2007-05-23 — — EP disclosed
JP-H09232288-A MANUFACTURE OF SEMICONDUCTOR DEVICE, AND RESIST MATERIAL HITACHI LTD 1997-09-05 — — JP disclosed
EP-0378430-B1 Novel organosilicon compound and process for producing organosilicon compound AGENCY IND SCIENCE TECHN (JP) 1995-02-01 — — EP disclosed
US-5151538-A ORGANOSILICON COMPOUND AND PROCESS FOR PRODUCING ORGANOSILICON COMPOUND AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1992-09-29 — — US disclosed
EP-0378430-A1 Novel organosilicon compound and process for producing organosilicon compound DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1990-07-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288327-A1 PROCESS FOR THE MANUFACTURE OF COMPOUNDS COMPRISING NITRILE FUNCTIONAL GROUPS NIT2, LPO, CNDP2 ESR1 3743/4885ESR2 4293/4885NR1H2 3928/4885
US-20120004440-A1 PROCESS FOR PRODUCING COMPOUNDS COMPRISING NITRILE FUNCTIONS NANP, NIT2, LPO ESR1 3287/4885ESR2 4353/4885NR1H2 3465/4885
US-20070260026-A1 Catalyst for Olefin Polymerization Process for Producing Olefin Polymer, Olefin Copolymer, Novel Transition Metal Compound, and Process for Producing Transition Metal Compound POF1B, RB1, CCNA1 ESR1 405/4885ESR2 266/4885NR1H2 526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.