Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8894684 | 0.98 | KDM4C (0.56) | KDM4CKMT2AHSD17B10MEN1CASP1 | |
| SCHEMBL8894176 | 0.83 | POLB (0.46) | KDM4CKMT2AHSD17B10MEN1CASP1 | |
| Hydrochloric Acid SCHEMBL8892491 | 0.82 | POLB (0.45) | KDM4CKMT2AHSD17B10MEN1CASP1 | |
| SCHEMBL8893610 | 0.82 | KDM4C (0.45) | KDM4CKMT2AHSD17B10MEN1CASP1 | |
| SCHEMBL8893397 | 0.81 | KDM4C (0.42) | KDM4CKMT2AHSD17B10MEN1CASP1 | |
| Hydrochloric Acid SCHEMBL8893221 | 0.81 | KDM4C (0.44) | KDM4CKMT2AHSD17B10MEN1CASP1 | |
| SCHEMBL8892830 | 0.79 | GAA (0.54) | KDM4CKMT2AHSD17B10MEN1CASP1 | |
| SCHEMBL9594535 | 0.75 | KDM4C (0.53) | KDM4CKMT2AHSD17B10MEN1CASP1 | |
| SCHEMBL409370 | 0.73 | NR3C2 (0.57) | KDM4CHSD17B10NR3C2APAF1CASP3 | |
| SCHEMBL6567347 | 0.73 | NR3C2 (0.57) | KDM4CHSD17B10NR3C2APAF1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654298-A | QUARTERNARY SALTS OF 4-AMINO-SUBSTITUTED PYRIDINES; MODULATORS OF THE SINOATRIAL NODE; CARDIOTONIC AND BRADYCARDIA AGENTS; | IMPERIAL CHEMICAL INDUSTRIES (GB) | 1997-08-05 | — | — | US | disclosed |
| EP-0453197-B1 | Amine derivatives | ICI PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| EP-0453197-A1 | Amine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-23 | — | — | EP | disclosed |