Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.64 |
| ▸ | DGKA | P23743 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895625 | 1.00 | NAAA (0.64) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL7836016 | 1.00 | NAAA (0.64) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL7837074 | 1.00 | NAAA (0.64) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL5634633 | 1.00 | NAAA (0.64) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL5065160 | 1.00 | NAAA (0.64) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL1569309 | 1.00 | NAAA (0.64) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL7838932 | 1.00 | NAAA (0.64) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL8896172 | 1.00 | NAAA (0.64) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL2049673 | 0.98 | NAAA (0.61) | NAAADGKAHTR2CPRSS1PRSS2 | |
| SCHEMBL126972 | 0.92 | DGKA (0.57) | NAAADGKAHTR2CPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |