Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895862 | 0.98 | LMNA (0.59) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL6972131 | 0.94 | LMNA (0.68) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL3364047 | 0.86 | HCAR2 (0.58) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL982156 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL1553490 | 0.85 | LMNA (0.65) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL21681731 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL21681730 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL1836828 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL21681727 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2NPC1RECQLRAB9A | |
| SCHEMBL21681726 | 0.83 | LMNA (0.62) | LMNASMN1; SMN2NPC1RECQLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |