Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8898012 | 0.88 | MEN1 (0.48) | MEN1KMT2AMAOBPTPN1PDK1 | |
| SCHEMBL14002243 | 0.87 | MAOB (0.59) | MEN1KMT2AMAOBALDH1A1HTT | |
| SCHEMBL2011849 | 0.86 | MEN1 (0.65) | MEN1KMT2AMAOBPTPN1ALDH1A1 | |
| SCHEMBL13599949 | 0.86 | MEN1 (0.49) | MEN1KMT2AMAOBPDK1PDK2 | |
| SCHEMBL27797837 | 0.84 | MEN1 (0.45) | MEN1KMT2AMAOBPDK1PDK2 | |
| SCHEMBL7419857 | 0.84 | GRM5 (0.51) | MEN1KMT2AMAOBSMN1; SMN2 | |
| SCHEMBL3718587 | 0.83 | LTB4R (0.52) | MEN1KMT2ANR4A2NR4A1NR4A3 | |
| SCHEMBL89330 | 0.82 | LMNA (0.55) | MEN1KMT2AMAOBPTPN1PDK1 | |
| SCHEMBL289919 | 0.81 | KMT2A (0.47) | MEN1KMT2ASMN1; SMN2ALOX5PTGS1 | |
| SCHEMBL1592632 | 0.81 | MEN1 (0.47) | MEN1KMT2AMAOBPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712493-A4 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMA CORP (US) | 1997-01-15 | — | — | EP | disclosed |
| EP-0712493-A1 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMACEUTICALS CORPORATION (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004277-A1 | A METHOD FOR PREPARING AND SELECTING PHARMACEUTICALLY USEFUL NON-PEPTIDE COMPOUNDS FROM A STRUCTURALLY DIVERSE UNIVERSAL LIBRARY | SPHINX PHARMACEUTICALS CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |