SCHEMBL8896525

SCHEMBL8896525

CCC(C)OC(=O)N(C(=O)[C@@H](N)C(C)C)C(C)c1cc2cc(Cl)ccc2o1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.51
TAS1R3 Q7RTX0 2/20 0.41
TAS1R1 Q7RTX1 2/20 0.41
TSHR P16473 1/20 0.36
KDM4E B2RXH2 3/20 0.35
MAOB P27338 3/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HRH4 Q9H3N8 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
GPR35 Q9HC97 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8896432 0.74 CA12 (0.44) ALOX5MAOBSMN1; SMN2ALDH1A1MEN1
SCHEMBL8898675 0.69 ALOX5 (0.38) ALOX5
SCHEMBL8896867 0.69 ALOX5 (0.58) ALOX5TAS1R3TAS1R1TSHRKDM4E
SCHEMBL8896522 0.69 TAS1R3 (0.44) ALOX5TAS1R3TAS1R1TSHRKDM4E
SCHEMBL8899224 0.69 POLB (0.40) ALOX5MAOBSMN1; SMN2ALDH1A1MEN1
SCHEMBL2395181 0.68 ALOX5 (1.00) ALOX5KDM4EMAOBSMN1; SMN2HSD17B10
SCHEMBL9411123 0.68 ALOX5 (0.41) ALOX5TAS1R3TAS1R1TSHRKDM4E
SCHEMBL8498815 0.68 ALOX5 (0.53) ALOX5TAS1R3TAS1R1TSHRKDM4E
SCHEMBL8060779 0.68 ALOX5 (0.59) ALOX5TAS1R3TAS1R1KDM4EMAOB
Hydrochloric Acid SCHEMBL8897585 0.67 ALOX5 (0.52) ALOX5TAS1R3TAS1R1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587110-B1 Condensed heterocyclic derivatives and agricultural or horticultural fungicides containing the same KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-12-17 EP claimed